Mesoestetic Melan Tran3x Daily Depigmenting Gel Cream – Review

Hydroquinone is disappearing from the OTC market in America, and some of you may be affected by the change, but do not worry, I’ve got you covered. This product from Mesoestetic can help you with hyperpigmentation issues.

The formula contains various ingredients with varying purposes, which give a gleaming and clear complexion. The star of the show is tranexamic acid at the concentration of 3% (I have discussed TXA before Shiseido and Sesderma); it helps with inflammation, hyperpigmentation, and redness. We also have 3% of the stalwart niacinamide, which works phenomenally well with TXA to brighten skin. On top of that, we have the Tyr Control Complex, a blend of kojic acid, a potent ingredient against hyperpigmentation, with a type of amino acid and a peptide, together they inhabit tyrosine oxidation and effectively prevents blemishes from coming into being. Moreover, the formula includes the Hydroxiacid Complex, an amalgam of salicylic acid and lactic acid to gently exfoliate skin and regulate its functions. We can also find the Marine glycogen, which protects from electromagnetic waves and blue light emitted by technological devices. It seems like a good addition considering how much time we spent in front of screens. Of course, the product contains common ingredients that we find in a moisturiser, such as glycerine and dimethicone, but do not fret. Despite all the emollients, the texture is pretty lightweight. The product has fragrance in its formula. Though it doesn’t seem like there’s a lot of it, the product smells medicinal. A lot is going on in the product, but does it work?

I have been using this product for three months now, and the results have been extraordinary. This product is a liquid eraser, which with continuous usage, imparts a brighter and healthier-looking appearance. Hyperpigmentation fades within days, and I have noticed some slight improvement with my odd redness (described here). However, I will seek professional treatments for that. Thanks to the exfoliating acids in this product, you can kill two birds with one stone and skip any additional exfoliants as your skin won’t need them. This cream fantastically removes dead skin cells and promotes smooth and glowing skin while keeping spots at bay. After using this cream every other day for about a month, I started to get compliments on the look of my skin because it genuinely started to glow. I don’t even have to use it every day to see the results; I apply it three to four times a week at nighttime. It has also helped me to pare back on my routine, as this is a multi-tasking product—radiant skin in just a few steps, no need for elaborate skincare regimens. 

This product is advised as a maintenance treatment after professional depigmenting therapies or on its own; I think the first part refers more to people who struggle with chronic or hormonal discolouration issues. However, I would recommend this product to everyone who grapples with hyperpigmentation. It must surely be worth a try if you cope with discolouration left by sun damage or acne because it will have a visible effect on pigmentation spots, and it can prevent breakouts. But, don’t use it as an acne treatment; it isn’t suited for that. You will only waste your money. 

This is a terrific product that truly transforms the skin; it makes your skin look perkier and brighter. The cream does what it says on the tin. It is suitable for all skin types, but I would caution people with sensitive skin or skin not accustomed to acid exfoliants as the product is quite robust, so introduce it slowly. If you feel like your hyperpigmentation will need a bigger kick to go away. In that case, you can pair this cream with other treatments that contain brightening ingredients like azelaic acid or ascorbic acid, or even a retinoid. 

Ingredients: Water, Isodecyl Neopentanoate, Butylene Glycol, Tranexamic acid, Niacinamide, Glycerine, Isostearyl AlcoholPolymethylsilsesquioxane, Sodium Citrate, Jojoba Esters, Butylene Glycol Cocoate, Caprylic/Capric Triglyceride, Isononyl Isononanoate, Polyacrylate Crosspolymer-6,  Helianthus annuus Seed Wax, Lactic acid, Argania spinosa Kernel Oil, Kojic acid, Salicylic acid, Aminoethylphosphinic acid, Glycogen, Acetyl Glycyl beta-Alanine, Acacia decurrens Flower Wax, Polyglycerin-3, Polyacrylate-13, Dimethicone, Polyisobuten, Ethylhexylglycerin, Sorbitan Isostearate, Ethylcellulose, Polysorbate 20, Sodium Hydroxide, Citric acid, Sodium Metabisulfite, BHT, Disodium EDTA, Phenoxyethanol, Parfum. (packaging) 

The Melan Tran3x Daily Depigmenting Gel Cream is available from Mesoestetic’s stockists worldwide.

4 responses to “Mesoestetic Melan Tran3x Daily Depigmenting Gel Cream – Review”

  1. Hi,

    Have you tried the Paula’s Choice Clinical Discolouration Repair Serum? I just started using it, and it seems to have somewhat similar ingredients.

    • Hi, I haven’t tried the Paula’s Choice Clinical Discolouration Repair Serum. PC’s serum and the Mesoestetic cream are somewhat similar indeed, but PC’s serum contains only tranexamic acid and niacinamide as the brightening ingredients. The Mesoestetic product in addition to the two ingredients contains lactic acid, kojic acid, and salicylic acid. The first two have a well-established track record as pigment reducing agents. Though, PC’s serum should yield some positive results.

  2. Thank you for replying.

    That’s good to know. So far, the Paula’s Choice has definitely faded a sun spot/freckle on my face significantly. So I will continue with it for now, since I already have it, and see how it goes. It would be interesting if the Mesoestetic would produce more dramatic results. I will keep it in mind.

    • My pleasure!

      I think you should give the PC serum some time, and you will see a difference. Depending on where you live, even though it’s winter in the Northern Hemisphere, you may still consider using sun protection, especially if you spend time in the mountains where you are more prone to sun damage. I’d recommend incorporating some type of sun protection with iron oxides like a BB cream or a foundation because iron oxides help to prevent the formation of sunspots caused by visible light.

      You may also consider adding an exfoliant with glycolic acid to your regimen to bolster the effects of the PC serum, e.g. the Neostrata Gel Plus (my review) or the Neostrata Gel Plus Salicylic (my review). There’s also another product from Neostrata, the Pigment Lightening Gel, which combines glycolic acid with kojic acid – I haven’t reviewed it yet; it’s good, but if you’re not used to acids, it may be a bit too much.

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